Acute prostatitis is treated with antibiotics. In severe cases, antibiotics will be given intravenously (into a vein). In less severe cases, antibiotics can be taken orally. Because it is difficult for antibiotics to get from the bloodstream into the prostate, these medications often are prescribed for three or more weeks.
If you are severely ill with prostatitis, your doctor may admit you to a hospital to give you intravenous antibiotics and make sure your vital signs remain stable. Usually, a stay of only a few days is needed. If the prostate is very swollen, it may be necessary to insert a catheter to allow urine to drain. This catheter may need to be left in place for up to a week, but as the infection comes under control, you should be able to urinate normally again.