Your doctor will ask about your sexual history, including new partners and condom use. Your doctor will look for an abnormal discharge from your urethra. In women, a pelvic examination will be done to look for tenderness, redness or abnormal discharge from the cervix and vagina. Because urethritis usually is caused by sexually transmitted infections, your doctor will examine you for signs of these, including syphilis, human papilloma virus (HPV), which causes venereal warts, and HIV
Urethritis caused by injury or chemical irritation is diagnosed based on your medical history and the absence of an infectious cause.